The medial temporal lobe memory system

The medial temporal lobe memory system.

Studies of human amnesia and studies of an animal model of human amnesia in the monkey have identified the anatomical components of the brain system for memory in the medial temporal lobe and have illuminated its function. This neural system consists of the hippocampus and adjacent, anatomically related cortex, including entorhinal, perirhinal, and parahippocampal cortices. These structures, pr...

Functional neuroanatomy of the medial temporal lobe memory system.

The Medial Temporal Lobe and Memory

Memory is a central component of our cognitive lives, and it is accomplished by multiple neurobiological memory systems that encode, retain, and retrieve different forms of information about past experience. Memory for the past can be used to build predictive models in the present and thus can guide current thoughts, decisions, and actions. For example, memory enables us to discriminate novel p...

The medial temporal lobe and recognition memory.

The ability to recognize a previously experienced stimulus is supported by two processes: recollection of the stimulus in the context of other information associated with the experience, and a sense of familiarity with the features of the stimulus. Although familiarity and recollection are functionally distinct, there is considerable debate about how these kinds of memory are supported by regio...

Medial temporal lobe and topographical memory.

There has been interest in the idea that medial temporal lobe (MTL) structures might be especially important for spatial processing and spatial memory. We tested the proposal that the MTL has a specific role in topographical memory as assessed in tasks of scene memory where the viewpoint shifts from study to test. Building on materials used previously for such studies, we administered three dif...